Polypeptide is a kind of compound which is made up of many amino acids connected by peptide bond.
In the late 1980s, Europe and America took the lead in the industrialized production of polypeptide raw materials based on solid-phase synthesis technology.
At present, the raw excipients used in the production of solid-phase peptide synthesis raw materials are mostly produced in China.
The Fmoc method is a new method for solid phase synthesis of peptides developed by Carpino and Hart based on the Boc method.
The Boc/Bzl method is a classical peptide solid phase synthesis method in which Boc is used as a temporary protecting group in combination with a benzylic semi-permanent side chain protecting group.
Polypeptide synthesis on a solid support, a concept of originality pioneered by Robert Bruce M errifield in 1963, is a major breakthrough in peptide chemistry.