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BIO-PHARMACEUTICAL & LIFE SCIENCE
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Typical Cases

Separation And Purification Of Vitamin B12
Extraction of Cephalosporin C

Industry

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Bio-Pharmaceutical & Life Science

Antibiotic purification; Peptide antibiotic synthesis; Enzyme-catalyzed reaction; Chromatographic separation
Modern biopharmaceutical technologies typically use biological microbial fermentation processes, enzyme-catalyzed reactions, or biologically metabolites obtained by cell culture. Biosynthesis technology can produce many active substances, such as antibodies, antibiotics, etc., but the concentration of biologically active substances is very low, and some is easy to be inactivate, the content of impurities is very high, and many impurities and targets have similar physical and chemical properties, which result Separation and purification difficult.
Sunresin's large pharmaceutical research and development department has proposed different solutions to various problems arising in the biopharmaceutical process through an in-depth understanding of the upstream and downstream industries of biopharmaceuticals. So far, many of our products have been successfully used in the Chinese market.
Our Advantages
  • Upstream and downstream multi-point solutions for the biopharmaceutical industry
  • High-standard resin production line special for the pharmaceutical industry
  • Technical supporting
Our Technique for Bio-pharmaceutical & Life Science
  • Peptide antibiotic synthesis--solid phase peptide synthesis
The initial peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa.

Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex Peptide.
 
  • Enzyme-catalyzed reaction--immobilized enzyme carrier
The enzyme immobilization technique is to immobilize the free enzyme on a solid support by physical or chemical means, and it needs to keep the same activity as the free enzyme.
 
  • Bio-pharmaceuticals separation--Ion exchange and adsorption Resin & system
Ion exchange and adsorption method is a cost-efficient separation technique that has been widely used in the pharmaceutical industry. It is primarily a way to achieve separation and purification on a large scale with ion exchange systems with complex and designable ion exchange resins. It removes impurities, concentrates the target, and produces highly pure pharmaceuticals.
 
  • Chromatographic separation--chromatography media
Separation of pharmaceuticals is often a very complex process, especially for substances with similar structures, such as isomers. At this time, it is necessary to perform high-purity pharmaceutical by means of chromatography separation.
Sunresin Techniques used in Bio-pharmaceutical Industry
Antibiotics Purification
Separation technique based on ion exchange & adsorbent system, for CephalosporinsC, aminoglycoside antibiotic, tocopherol, Polypeptide and proteins purification.
Immobilized Enzyme Carrier
As carrier for Enzyme-catalyzed Reaction, applied in manufacturing of 7ACA、6APA、7ADCA and amino acid.
Solid Phase Peptide Synthesis
Peptide antibiotics could be synthesized by SPPS.
Chromatography Media
Chromatography Separation is especially for substances with similar structures, such as isomers.

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Latest News

01 2020-12
A Better Choice for Tungsten and Molybdenum Separation

Sunresin has set up special topics and established a special research team based on customers’ needs to conduct research and analysis on the element composition and existing technology of tungsten leaching solution, and successfully developed sepcial resin Seplite® LSC680 for tungsten and molybdenum separation as well as the matching process.

27 2020-11
Acetone Purification and Cycling (Methylamine removal), solvent in the production of PPS (polyphenylene sulfide)

The ion exchange resin (IER) method is very excellent and efficient for acetone purification. Acetone will pass cation exchange resins first and then the anion exchange resins, more than 95% methylamine will be removed.

24 2020-11
Sunresin awarded as Asia's Best Under A Billion by Forbes 

On November 23, 2020,Forbes announced Asia’s Best Under A Billion 2019 list. Sunresin was honored to be selected. The promulgation ceremony originally scheduled to be held in Bangkok, Thailand, was carried out online due to continuous spreading pandemic.

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