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New Technoloy For Pharmaceutical Industry Nov 13, 2014

Nowadays,ion exchange resins are widely used in the manufacturing of pharmaceuticals, not only for

catalyzing certain reactions but also for isolating and purifying pharmaceutical active ingredients.

Three ion exchange resins, sodium polystyrene sulfonate,colestipol, and cholestyramine , are used

as active ingredients. Sodium polystyrene sulfonate is a strongly acidic ion exchange resin and is used

to treat hyperkalemia. Colestipol is a weakly basic ion exchange resin and is used to treat hypercholesterolemia. 

Cholestyramine is a strongly basic ion exchange resin and is also used to treat hypercholesterolemia.

Colestipol and cholestyramine are known as bile acid sequestrants.

Ion exchange resins are also used as excipients in pharmaceutical formulations such as tablets, capsules, gums,

and suspensions. In these uses the ion exchange resin can have several different functions, including

taste-masking, extended release, tablet disintegration, increased bioavailability, and improving the chemical

 stability of the active ingredients.